Search on: GENE PRODUCTS, NEF 
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Descriptor English:   Gene Products, nef 
Descriptor Spanish:   Productos del Gen nef 
Descriptor Portuguese:   Produtos do Gene nef 
Synonyms English:   3'-orf Protein
Gene Product, nef
3' orf Protein
nef Gene Product
nef Gene Products
nef Protein  
Tree Number:   D12.776.964.775.362
D12.776.964.925.500
Definition English:   Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor. 
History Note English:   91(90); was see under VIRAL REGULATORY PROTEINS 1990 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24676 
Unique Identifier:   D015693 

Occurrence in VHL:
 

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